1. Atropinize the patient immediately and maintain full atropinization by repeated doses of 2 to 4 mg. of atropine sulphate intravenously at 5 to 10 minutes interval. As much as 25 to 50 mg. of atropine may be required in a day. The need for further atropine administration is guided by the continuance of symptoms. Extent of salivation is a useful criterion for dose adjustment. 2. Disslove 1-2 gm of 2 PAM in 10 ml distilled water and inject intravenously very slowly for 10-15 minutes. 3. Antihistsamines may be given to control allergic manifestation.